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Infrequent mutation of the tumour-suppressor gene Smad4 in early-stage colorectal cancer
Smad4 is a candidate tumour-suppressor gene identified recently on chromosome 18q21.1. Both alleles are inactivated in nearly one-half of pancreatic carcinomas, but its role in the tumorigenesis of other tumours is still unknown. The aim of this study was to investigate the potential involvement of...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747552/ https://www.ncbi.nlm.nih.gov/pubmed/12569386 http://dx.doi.org/10.1038/sj.bjc.6600733 |