Tracking the cell cycle origins for escape from topotecan action by breast cancer cells

The anticancer agent topotecan is considered to be S-phase specific. This implies that cancer cells that are not actively replicating DNA could resist the effects of the drug. The cycle specificity of topotecan action was investigated in MCF-7 cells, using time-lapse microscopy to link the initial c...

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Detalles Bibliográficos
Autores principales: Feeney, G P, Errington, R J, Wiltshire, M, Marquez, N, Chappell, S C, Smith, P J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747574/
https://www.ncbi.nlm.nih.gov/pubmed/12698201
http://dx.doi.org/10.1038/sj.bjc.6600889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747574/
https://www.ncbi.nlm.nih.gov/pubmed/12698201
http://dx.doi.org/10.1038/sj.bjc.6600889

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