A human, compact, fully functional anti-ErbB2 antibody as a novel antitumour agent

A new human, compact antibody was engineered by fusion of a human, antitumour ErbB2-directed scFv with a human IgG1 Fc domain. Overexpression of the ErbB2 receptor is related to tumour aggressiveness and poor prognosis. This new immunoagent meets all criteria for a potential anticancer drug: it is h...

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Detalles Bibliográficos
Autores principales: De Lorenzo, C, Tedesco, A, Terrazzano, G, Cozzolino, R, Laccetti, P, Piccoli, R, D'Alessio, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747711/
https://www.ncbi.nlm.nih.gov/pubmed/15305184
http://dx.doi.org/10.1038/sj.bjc.6602110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747711/
https://www.ncbi.nlm.nih.gov/pubmed/15305184
http://dx.doi.org/10.1038/sj.bjc.6602110

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