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Abrogation of IL-6-mediated JAK signalling by the cyclopentenone prostaglandin 15d-PGJ(2) in oral squamous carcinoma cells

Cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) exerts antineoplastic effects on various types of human cancer. We recently showed that treatment with 15d-PGJ(2) induces apoptosis accompanied by downregulation of the oncogenic signal transducer and activator of transcription 3 (Stat...

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Detalles Bibliográficos
Autores principales: Siavash, H, Nikitakis, N G, Sauk, J J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747713/
https://www.ncbi.nlm.nih.gov/pubmed/15316561
http://dx.doi.org/10.1038/sj.bjc.6602055