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METH-2 silencing and promoter hypermethylation in NSCLC

The antiangiogenic factor METH-2 (ADAMTS-8) was identified in a previous dual-channel cDNA microarray analysis to be at least two-fold under-represented in 85% (28 out of 33) of primary non-small-cell lung carcinomas (NSCLCs). This observation has been validated in an independent series of NSCLCs an...

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Detalles Bibliográficos
Autores principales: Dunn, J R, Panutsopulos, D, Shaw, M W, Heighway, J, Dormer, R, Salmo, E N, Watson, S G, Field, J K, Liloglou, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747718/
https://www.ncbi.nlm.nih.gov/pubmed/15328519
http://dx.doi.org/10.1038/sj.bjc.6602107