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Ligand-regulated oligomerization of β(2)-adrenoceptors in a model lipid bilayer

The β(2)-adrenoceptor (β(2)AR) was one of the first Family A G protein-coupled receptors (GPCRs) shown to form oligomers in cellular membranes, yet we still know little about the number and arrangement of protomers in oligomers, the influence of ligands on the organization or stability of oligomers,...

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Detalles Bibliográficos
Autores principales: Fung, Juan José, Deupi, Xavier, Pardo, Leonardo, Yao, Xiao Jie, Velez-Ruiz, Gisselle A, DeVree, Brian T, Sunahara, Roger K, Kobilka, Brian K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748299/
https://www.ncbi.nlm.nih.gov/pubmed/19763081
http://dx.doi.org/10.1038/emboj.2009.267