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Design of protein-interaction specificity affords selective bZIP-binding peptides

Interaction specificity is a required feature of biological networks and a necessary characteristic of protein or small-molecule reagents and therapeutics. The ability to alter or inhibit protein interactions selectively would advance basic and applied molecular science. Assessing or modelling inter...

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Detalles Bibliográficos
Autores principales: Grigoryan, Gevorg, Reinke, Aaron W., Keating, Amy E.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748673/
https://www.ncbi.nlm.nih.gov/pubmed/19370028
http://dx.doi.org/10.1038/nature07885