AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice

In Alzheimer's disease tauopathy is considered secondary to amyloid, and the duality obscures their relation and the definition of their respective contributions. Transgenic mouse models do not resolve this problem conclusively, i.e. the relative hierarchy of amyloid and tau pathology depends o...

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Detalles Bibliográficos
Autores principales: Jaworski, Tomasz, Dewachter, Ilse, Lechat, Benoit, Croes, Sophie, Termont, Annelies, Demedts, David, Borghgraef, Peter, Devijver, Herman, Filipkowski, Robert K., Kaczmarek, Leszek, Kügler, Sebastian, Van Leuven, Fred
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748684/
https://www.ncbi.nlm.nih.gov/pubmed/19794916
http://dx.doi.org/10.1371/journal.pone.0007280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748684/
https://www.ncbi.nlm.nih.gov/pubmed/19794916
http://dx.doi.org/10.1371/journal.pone.0007280

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