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Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines

A two step synthesis of 2-alkynyl-4-arylquinolines has been accomplished via Pd/C-mediated regioselective C-2 alkynylation of 2,4-dichloroquinoline in water followed by Suzuki coupling at C-4 of the resulting 4-chloro derivative.

Detalles Bibliográficos
Autores principales: Reddy, Ellanki Amarender, Islam, Aminul, Mukkanti, K, Bandameedi, Venkanna, Bhowmik, Dipal Ranjan, Pal, Manojit
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748691/
https://www.ncbi.nlm.nih.gov/pubmed/19777134
http://dx.doi.org/10.3762/bjoc.5.32