Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines

A two step synthesis of 2-alkynyl-4-arylquinolines has been accomplished via Pd/C-mediated regioselective C-2 alkynylation of 2,4-dichloroquinoline in water followed by Suzuki coupling at C-4 of the resulting 4-chloro derivative.

Detalles Bibliográficos
Autores principales: Reddy, Ellanki Amarender, Islam, Aminul, Mukkanti, K, Bandameedi, Venkanna, Bhowmik, Dipal Ranjan, Pal, Manojit
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2009
Materias:
Preliminary Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748691/
https://www.ncbi.nlm.nih.gov/pubmed/19777134
http://dx.doi.org/10.3762/bjoc.5.32
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author Reddy, Ellanki Amarender
Islam, Aminul
Mukkanti, K
Bandameedi, Venkanna
Bhowmik, Dipal Ranjan
Pal, Manojit
author_facet Reddy, Ellanki Amarender
Islam, Aminul
Mukkanti, K
Bandameedi, Venkanna
Bhowmik, Dipal Ranjan
Pal, Manojit
author_sort Reddy, Ellanki Amarender
collection PubMed
description A two step synthesis of 2-alkynyl-4-arylquinolines has been accomplished via Pd/C-mediated regioselective C-2 alkynylation of 2,4-dichloroquinoline in water followed by Suzuki coupling at C-4 of the resulting 4-chloro derivative.
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spelling pubmed-27486912009-09-23 Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines Reddy, Ellanki Amarender Islam, Aminul Mukkanti, K Bandameedi, Venkanna Bhowmik, Dipal Ranjan Pal, Manojit Beilstein J Org Chem Preliminary Communication A two step synthesis of 2-alkynyl-4-arylquinolines has been accomplished via Pd/C-mediated regioselective C-2 alkynylation of 2,4-dichloroquinoline in water followed by Suzuki coupling at C-4 of the resulting 4-chloro derivative. Beilstein-Institut 2009-07-01 /pmc/articles/PMC2748691/ /pubmed/19777134 http://dx.doi.org/10.3762/bjoc.5.32 Text en Copyright © 2009, Reddy et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Preliminary Communication
Reddy, Ellanki Amarender
Islam, Aminul
Mukkanti, K
Bandameedi, Venkanna
Bhowmik, Dipal Ranjan
Pal, Manojit
Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines
title Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines
title_full Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines
title_fullStr Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines
title_full_unstemmed Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines
title_short Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines
title_sort regioselective alkynylation followed by suzuki coupling of 2,4-dichloroquinoline: synthesis of 2-alkynyl-4-arylquinolines
topic Preliminary Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748691/
https://www.ncbi.nlm.nih.gov/pubmed/19777134
http://dx.doi.org/10.3762/bjoc.5.32
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