Cargando…

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

Toll-like receptors (TLRs) play a pivotal role in innate immunity and inflammation. Here we showed that genetic deficiency of Peli1, an E3 ubiquitin ligase, attenuates induction of proinflammatory cytokines by ligands of TLR3 and TLR4 and renders mice resistant to septic shock. Peli1 was required fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Mikyoung, Jin, Wei, Sun, Shao-Cong
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748822/ https://www.ncbi.nlm.nih.gov/pubmed/19734906 http://dx.doi.org/10.1038/ni.1777

Ejemplares similares

Beyond MyD88 and TRIF Pathways in Toll-Like Receptor Signaling
por: Piras, Vincent, et al.
Publicado: (2014)

The Toll-Like receptor adaptor TRIF contributes to otitis media pathogenesis and recovery
por: Leichtle, Anke, et al.
Publicado: (2009)

Peli1 negatively regulates T-cell activation and prevents autoimmunity
por: Chang, Mikyoung, et al.
Publicado: (2011)

Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway
por: Zhang, Xuedan, et al.
Publicado: (2022)

Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation
por: Xiao, Yichuan, et al.
Publicado: (2013)

Peli1 signaling blockade attenuates congenital zika syndrome
por: Luo, Huanle, et al.
Publicado: (2020)

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9–driven antiinflammatory cytokine production
por: González-Navajas, Jose M., et al.
Publicado: (2010)

Effects of Toll-like Receptor Ligands on the Expression of Proinflammatory Cytokines and Avian β-defensins in Cultured Chick Intestine
por: Terada, Takumi, et al.
Publicado: (2020)

IRF3 Negatively Regulates Toll-Like Receptor-Mediated NF-κB Signaling by Targeting TRIF for Degradation in Teleost Fish
por: Zhao, Xueyan, et al.
Publicado: (2018)

Anti-Inflammatory Action of an Antimicrobial Model Peptide That Suppresses the TRIF-Dependent Signaling Pathway via Inhibition of Toll-Like Receptor 4 Endocytosis in Lipopolysaccharide-Stimulated Macrophages
por: Shim, Do-Wan, et al.
Publicado: (2015)

Immunohistochemical Analysis of Toll-Like Receptors, MyD88, and TRIF in Human Papillary Thyroid Carcinoma and Anaplastic Thyroid Carcinoma
por: Nihon-Yanagi, Yasuhiro, et al.
Publicado: (2021)

Melatonin Suppresses Toll Like Receptor 4-Dependent Caspase-3 Signaling Activation Coupled with Reduced Production of Proinflammatory Mediators in Hypoxic Microglia
por: Yao, Linli, et al.
Publicado: (2016)

Peli1 negatively regulates type I interferon induction and antiviral immunity in the CNS
por: Xiao, Yichuan, et al.
Publicado: (2015)

Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection
por: Totura, Allison L., et al.
Publicado: (2015)

Epigallocatechin-3-gallate suppresses proinflammatory cytokines and chemokines induced by Toll-like receptor 9 agonists in prostate cancer cells
por: Mukherjee, Sushovita, et al.
Publicado: (2014)

Stable Toll-Like Receptor 10 Knockdown in THP-1 Cells Reduces TLR-Ligand-Induced Proinflammatory Cytokine Expression
por: Le, Hai Van, et al.
Publicado: (2016)

Leptospiral Hemolysins Induce Proinflammatory Cytokines through Toll-Like Receptor 2-and 4-Mediated JNK and NF-κB Signaling Pathways
por: Wang, Huan, et al.
Publicado: (2012)

Formal Modelling of Toll like Receptor 4 and JAK/STAT Signalling Pathways: Insight into the Roles of SOCS-1, Interferon-β and Proinflammatory Cytokines in Sepsis
por: Paracha, Rehan Zafar, et al.
Publicado: (2014)

Pathophysiological Commonality Between Irritable Bowel Syndrome and Metabolic Syndrome: Role of Corticotropin-releasing Factor–Toll-like Receptor 4–Proinflammatory Cytokine Signaling
por: Nozu, Tsukasa, et al.
Publicado: (2022)

Der p2 Internalization by Epithelium Synergistically Augments Toll-like Receptor-Mediated Proinflammatory Signaling
por: Yin, Sui-Chu, et al.
Publicado: (2015)

Correction to Figures: A Reply to Hwang and Peli (2014)
por: Gao, Zhongpai
Publicado: (2017)

Regulation of RIP3 protein stability by PELI1-mediated proteasome-dependent degradation
por: Park, Han-Hee, et al.
Publicado: (2018)

Age-Dependent Maturation of Toll-Like Receptor-Mediated Cytokine Responses in Gambian Infants
por: Burl, Sarah, et al.
Publicado: (2011)

Differential Regulation of Toll-Like Receptor-Mediated Cytokine Production by Unfolded Protein Response
por: Kim, Sena, et al.
Publicado: (2018)

The flagellin/Toll-like receptor 5 axis elicits diffuse proinflammatory signaling and innate immune defenses in vivo
por: Rolli, Joelle, et al.
Publicado: (2008)

Toll-Like Receptor 3/TRIF-Dependent IL-12p70 Secretion Mediated by Streptococcus pneumoniae RNA and Its Priming by Influenza A Virus Coinfection in Human Dendritic Cells
por: Spelmink, Laura, et al.
Publicado: (2016)

Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus
por: Liu, Junli, et al.
Publicado: (2018)

The Brain Proteome of the Ubiquitin Ligase Peli1 Knock-Out Mouse during Experimental Autoimmune Encephalomyelitis
por: Lereim, Ragnhild Reehorst, et al.
Publicado: (2016)

Normal Human Gingival Epithelial Cells Sense C. parapsilosis by Toll-Like Receptors and Module Its Pathogenesis through Antimicrobial Peptides and Proinflammatory Cytokines
por: Bahri, Raouf, et al.
Publicado: (2010)

PELI1 and EGFR cooperate to promote breast cancer metastasis
por: Qi, Jie, et al.
Publicado: (2023)

Preferences for everyday living inventory (PELI): study protocol for piloting a culture-sensitive and setting-specific translated instrument in German care settings (PELI-D)
por: Stacke, Tobias Ingo, et al.
Publicado: (2020)

Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages
por: Karimi, Khalil, et al.
Publicado: (2006)

The Number of X Chromosomes Influences Inflammatory Cytokine Production Following Toll-Like Receptor Stimulation
por: Lefèvre, Nicolas, et al.
Publicado: (2019)

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
por: Fitzgerald, Katherine A., et al.
Publicado: (2003)

Calcitriol May Down-Regulate mRNA Over-Expression of Toll-Like Receptor-2 and -4, LL-37 and Proinflammatory Cytokines in Cultured Human Keratinocytes
por: Jeong, Mi Sook, et al.
Publicado: (2014)

Effects of Diets Enriched in Linseed and Fish Oil on the Expression Pattern of Toll-Like Receptors 4 and Proinflammatory Cytokines on Gonadal Axis and Reproductive Organs in Rabbit Buck
por: Menchetti, Laura, et al.
Publicado: (2020)

Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
por: Jin, Jing-Ji, et al.
Publicado: (2008)

Liposomal Lipopolysaccharide Initiates TRIF-Dependent Signaling Pathway Independent of CD14
por: Watanabe, Sachiko, et al.
Publicado: (2013)

TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis
por: Tang, Yiting, et al.
Publicado: (2018)

Role of Cytokines and Toll-Like Receptors in the Immunopathogenesis of Guillain-Barré Syndrome
por: Nyati, Kishan Kumar, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_rj2c3cunc8g9avsmnha2gb1tdv