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The hereditary spastic paraplegia proteins NIPA1, spastin and spartin are inhibitors of mammalian BMP signalling

The hereditary spastic paraplegias (HSPs) are genetic conditions characterized by distal axonopathy of the longest corticospinal tract axons, and so their study provides an important opportunity to understand mechanisms involved in axonal maintenance and degeneration. A group of HSP genes encode pro...

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Detalles Bibliográficos
Autores principales: Tsang, Hilda T.H., Edwards, Thomas L., Wang, Xinnan, Connell, James W., Davies, Rachel J., Durrington, Hannah J., O'Kane, Cahir J., Luzio, J. Paul, Reid, Evan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748891/
https://www.ncbi.nlm.nih.gov/pubmed/19620182
http://dx.doi.org/10.1093/hmg/ddp324