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The hereditary spastic paraplegia proteins NIPA1, spastin and spartin are inhibitors of mammalian BMP signalling
The hereditary spastic paraplegias (HSPs) are genetic conditions characterized by distal axonopathy of the longest corticospinal tract axons, and so their study provides an important opportunity to understand mechanisms involved in axonal maintenance and degeneration. A group of HSP genes encode pro...
Autores principales: | Tsang, Hilda T.H., Edwards, Thomas L., Wang, Xinnan, Connell, James W., Davies, Rachel J., Durrington, Hannah J., O'Kane, Cahir J., Luzio, J. Paul, Reid, Evan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748891/ https://www.ncbi.nlm.nih.gov/pubmed/19620182 http://dx.doi.org/10.1093/hmg/ddp324 |
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