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Human Y Chromosome Base-Substitution Mutation Rate Measured by Direct Sequencing in a Deep-Rooting Pedigree

Understanding the key process of human mutation is important for many aspects of medical genetics and human evolution. In the past, estimates of mutation rates have generally been inferred from phenotypic observations or comparisons of homologous sequences among closely related species [1–3]. Here,...

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Detalles Bibliográficos
Autores principales: Xue, Yali, Wang, Qiuju, Long, Quan, Ng, Bee Ling, Swerdlow, Harold, Burton, John, Skuce, Carl, Taylor, Ruth, Abdellah, Zahra, Zhao, Yali, MacArthur, Daniel G., Quail, Michael A., Carter, Nigel P., Yang, Huanming, Tyler-Smith, Chris
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748900/
https://www.ncbi.nlm.nih.gov/pubmed/19716302
http://dx.doi.org/10.1016/j.cub.2009.07.032