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Human Y Chromosome Base-Substitution Mutation Rate Measured by Direct Sequencing in a Deep-Rooting Pedigree
Understanding the key process of human mutation is important for many aspects of medical genetics and human evolution. In the past, estimates of mutation rates have generally been inferred from phenotypic observations or comparisons of homologous sequences among closely related species [1–3]. Here,...
Autores principales: | Xue, Yali, Wang, Qiuju, Long, Quan, Ng, Bee Ling, Swerdlow, Harold, Burton, John, Skuce, Carl, Taylor, Ruth, Abdellah, Zahra, Zhao, Yali, MacArthur, Daniel G., Quail, Michael A., Carter, Nigel P., Yang, Huanming, Tyler-Smith, Chris |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748900/ https://www.ncbi.nlm.nih.gov/pubmed/19716302 http://dx.doi.org/10.1016/j.cub.2009.07.032 |
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