Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14

Grb7, Grb10 and Grb14 are adapter proteins containing a Ras-associating (RA) domain, a pleckstrin-homology (PH) domain, a family-specific BPS (between PH and SH2) region, and a C-terminal Src-homology-2 domain. Previous structural studies showed that the Grb14 BPS region binds as a pseudosubstrate i...

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Detalles Bibliográficos
Autores principales: Depetris, Rafael S, Wu, Jinhua, Hubbard, Stevan R
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748937/
https://www.ncbi.nlm.nih.gov/pubmed/19648926
http://dx.doi.org/10.1038/nsmb.1642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748937/
https://www.ncbi.nlm.nih.gov/pubmed/19648926
http://dx.doi.org/10.1038/nsmb.1642

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