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Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14
Grb7, Grb10 and Grb14 are adapter proteins containing a Ras-associating (RA) domain, a pleckstrin-homology (PH) domain, a family-specific BPS (between PH and SH2) region, and a C-terminal Src-homology-2 domain. Previous structural studies showed that the Grb14 BPS region binds as a pseudosubstrate i...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748937/ https://www.ncbi.nlm.nih.gov/pubmed/19648926 http://dx.doi.org/10.1038/nsmb.1642 |