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The promoter polymorphism -232C/G of the PCK1 gene is associated with type 2 diabetes in a UK-resident South Asian population

BACKGROUND: The PCK1 gene, encoding cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C), has previously been implicated as a candidate gene for type 2 diabetes (T2D) susceptibility. Rodent models demonstrate that over-expression of Pck1 can result in T2D development and a single nucleotide polymor...

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Detalles Bibliográficos
Autores principales: Rees, Simon D, Britten, Abigail C, Bellary, Srikanth, O'Hare, J Paul, Kumar, Sudhesh, Barnett, Anthony H, Kelly, M Ann
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749022/
https://www.ncbi.nlm.nih.gov/pubmed/19725958
http://dx.doi.org/10.1186/1471-2350-10-83