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The promoter polymorphism -232C/G of the PCK1 gene is associated with type 2 diabetes in a UK-resident South Asian population
BACKGROUND: The PCK1 gene, encoding cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C), has previously been implicated as a candidate gene for type 2 diabetes (T2D) susceptibility. Rodent models demonstrate that over-expression of Pck1 can result in T2D development and a single nucleotide polymor...
Autores principales: | Rees, Simon D, Britten, Abigail C, Bellary, Srikanth, O'Hare, J Paul, Kumar, Sudhesh, Barnett, Anthony H, Kelly, M Ann |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749022/ https://www.ncbi.nlm.nih.gov/pubmed/19725958 http://dx.doi.org/10.1186/1471-2350-10-83 |
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