Structural effects of clinically observed mutations in JAK2 exons 13-15: comparison with V617F and exon 12 mutations

BACKGROUND: The functional relevance of many of the recently detected JAK2 mutations, except V617F and exon 12 mutants, in patients with chronic myeloproliferative neoplasia (MPN) has been significantly overlooked. To explore atomic-level explanations of the possible mutational effects from those ov...

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Detalles Bibliográficos
Autores principales: Lee, Tai-Sung, Ma, Wanlong, Zhang, Xi, Kantarjian, Hagop, Albitar, Maher
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749040/
https://www.ncbi.nlm.nih.gov/pubmed/19744331
http://dx.doi.org/10.1186/1472-6807-9-58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749040/
https://www.ncbi.nlm.nih.gov/pubmed/19744331
http://dx.doi.org/10.1186/1472-6807-9-58

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