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Mitochondrial BNIP3 upregulation precedes endonuclease G translocation in hippocampal neuronal death following oxygen-glucose deprivation

BACKGROUND: Caspase-independent apoptotic pathways are suggested as a mechanism for the delayed neuronal death following ischemic insult. However, the underlying signalling mechanisms are largely unknown. Recent studies imply the involvement of several mitochondrial proteins, including endonuclease...

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Detalles Bibliográficos
Autores principales: Zhao, Shen-Ting, Chen, Ming, Li, Shu-Ji, Zhang, Ming-Hai, Li, Bo-Xing, Das, Manas, Bean, Jonathan C, Kong, Ji-Ming, Zhu, Xin-Hong, Gao, Tian-Ming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749049/
https://www.ncbi.nlm.nih.gov/pubmed/19737385
http://dx.doi.org/10.1186/1471-2202-10-113