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No association between a candidate TCF7L2 variant and risk of breast or ovarian cancer

BACKGROUND: TCF7L2 is a transcription factor involved in Wnt/β-catenin signaling which has a variant known to be associated with risk of Type 2 diabetes and, in some studies, with risk of certain cancers, including familial breast cancer. No studies of ovarian cancer have been reported to date. METH...

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Detalles Bibliográficos
Autores principales: Goode, Ellen L, Szabo, Csilla, Prokunina-Olsson, Ludmila, Vierkant, Robert A, Fredericksen, Zachary S, Collins, Francis S, White, Kristin L, Schmidt, Michele, Fridley, Brooke L, Couch, Fergus J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749057/
https://www.ncbi.nlm.nih.gov/pubmed/19732438
http://dx.doi.org/10.1186/1471-2407-9-312