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Par-3 partitioning defective 3 homolog (C. elegans) and androgen-induced prostate proliferative shutoff associated protein genes are mutationally inactivated in prostate cancer cells

BACKGROUND: Gene identification by nonsense-mediated mRNA decay inhibition (GINI) has proven its usefulness in identifying mutant genes in cancer cell lines. An increase in transcription in response to NMD inhibition of a subset of genes is a major cause of false positives when genes are selected fo...

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Detalles Bibliográficos
Autores principales: Kunnev, Dimiter, Ivanov, Igor, Ionov, Yurij
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749059/
https://www.ncbi.nlm.nih.gov/pubmed/19737411
http://dx.doi.org/10.1186/1471-2407-9-318