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Characterization and Inhibition of a Class II Diterpene Cyclase from Mycobacterium tuberculosis: IMPLICATIONS FOR TUBERCULOSIS

Mycobacterium tuberculosis remains a widespread and devastating human pathogen, whose ability to infiltrate macrophage host cells from the human immune system is an active area of investigation. We have recently reported the discovery of a novel diterpene from M. tuberculosis, edaxadiene, whose abil...

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Detalles Bibliográficos
Autores principales: Mann, Francis M., Prisic, Sladjana, Hu, Huayou, Xu, Meimei, Coates, Robert M., Peters, Reuben J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749132/
https://www.ncbi.nlm.nih.gov/pubmed/19574210
http://dx.doi.org/10.1074/jbc.M109.023788