Non-Redundant Role for IL-12 and IL-27 in Modulating Th2 Polarization of Carcinoembryonic Antigen Specific CD4 T Cells from Pancreatic Cancer Patients

BACKGROUND: Pancreatic cancer is a very aggressive disease with dismal prognosis; peculiar is the tumor microenvironment characterized by an extensive fibrotic stroma, which favors rapid tumor progression. We previously reported that pancreatic cancer patients have a selective Th2 skew in the anti-c...

Descripción completa

Detalles Bibliográficos
Autores principales: Tassi, Elena, Braga, Marco, Longhi, Renato, Gavazzi, Francesca, Parmiani, Giorgio, Di Carlo, Valerio, Protti, Maria Pia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749205/
https://www.ncbi.nlm.nih.gov/pubmed/19798410
http://dx.doi.org/10.1371/journal.pone.0007234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749205/
https://www.ncbi.nlm.nih.gov/pubmed/19798410
http://dx.doi.org/10.1371/journal.pone.0007234

Ejemplares similares