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Non-Redundant Role for IL-12 and IL-27 in Modulating Th2 Polarization of Carcinoembryonic Antigen Specific CD4 T Cells from Pancreatic Cancer Patients

BACKGROUND: Pancreatic cancer is a very aggressive disease with dismal prognosis; peculiar is the tumor microenvironment characterized by an extensive fibrotic stroma, which favors rapid tumor progression. We previously reported that pancreatic cancer patients have a selective Th2 skew in the anti-c...

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Detalles Bibliográficos
Autores principales:	Tassi, Elena, Braga, Marco, Longhi, Renato, Gavazzi, Francesca, Parmiani, Giorgio, Di Carlo, Valerio, Protti, Maria Pia
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749205/ https://www.ncbi.nlm.nih.gov/pubmed/19798410 http://dx.doi.org/10.1371/journal.pone.0007234

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