Analysis of Cancer Mutation Signatures in Blood by a Novel Ultra-Sensitive Assay: Monitoring of Therapy or Recurrence in Non-Metastatic Breast Cancer

BACKGROUND: Tumor DNA has been shown to be present both in circulating tumor cells in blood and as fragments in the plasma of metastatic cancer patients. The identification of ultra-rare tumor-specific mutations in blood would be the ultimate marker to measure efficacy of cancer therapy and/ or earl...

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Detalles Bibliográficos
Autores principales: Chen, Zhenbin, Feng, Jinong, Buzin, Carolyn H., Liu, Qiang, Weiss, Lawrence, Kernstine, Kemp, Somlo, George, Sommer, Steve S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749210/
https://www.ncbi.nlm.nih.gov/pubmed/19789704
http://dx.doi.org/10.1371/journal.pone.0007220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749210/
https://www.ncbi.nlm.nih.gov/pubmed/19789704
http://dx.doi.org/10.1371/journal.pone.0007220

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