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The Synthetic Plasmodium falciparum Circumsporozoite Peptide PfCS102 as a Malaria Vaccine Candidate: A Randomized Controlled Phase I Trial

BACKGROUND: Fully efficient vaccines against malaria pre-erythrocytic stage are still lacking. The objective of this dose/adjuvant-finding study was to evaluate the safety, reactogenicity and immunogenicity of a vaccine candidate based on a peptide spanning the C-terminal region of Plasmodium falcip...

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Detalles Bibliográficos
Autores principales: Audran, Régine, Lurati-Ruiz, Floriana, Genton, Blaise, Blythman, Hildur E., Ofori-Anyinam, Opokua, Reymond, Christophe, Corradin, Giampietro, Spertini, François
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749339/
https://www.ncbi.nlm.nih.gov/pubmed/19798415
http://dx.doi.org/10.1371/journal.pone.0007304