Functional Dissection of Streptococcus pyogenes M5 Protein: the Hypervariable Region is Essential for Virulence

The surface-localized M protein of Streptococcus pyogenes is a major virulence factor that inhibits phagocytosis, as determined ex vivo. Because little is known about the role of M protein in vivo we analyzed the contribution of different M protein regions to virulence, using the fibrinogen (Fg)-bin...

Descripción completa

Detalles Bibliográficos
Autores principales: Waldemarsson, Johan, Stålhammar-Carlemalm, Margaretha, Sandin, Charlotta, Castellino, Francis J., Lindahl, Gunnar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749438/
https://www.ncbi.nlm.nih.gov/pubmed/19794915
http://dx.doi.org/10.1371/journal.pone.0007279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749438/
https://www.ncbi.nlm.nih.gov/pubmed/19794915
http://dx.doi.org/10.1371/journal.pone.0007279

Ejemplares similares