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Functional Dissection of Streptococcus pyogenes M5 Protein: the Hypervariable Region is Essential for Virulence
The surface-localized M protein of Streptococcus pyogenes is a major virulence factor that inhibits phagocytosis, as determined ex vivo. Because little is known about the role of M protein in vivo we analyzed the contribution of different M protein regions to virulence, using the fibrinogen (Fg)-bin...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749438/ https://www.ncbi.nlm.nih.gov/pubmed/19794915 http://dx.doi.org/10.1371/journal.pone.0007279 |