Interactome Analyses Identify Ties of PrP(C) and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones

The physiological environment which hosts the conformational conversion of the cellular prion protein (PrP(C)) to disease-associated isoforms has remained enigmatic. A quantitative investigation of the PrP(C) interactome was conducted in a cell culture model permissive to prion replication. To facil...

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Detalles Bibliográficos
Autores principales: Watts, Joel C., Huo, Hairu, Bai, Yu, Ehsani, Sepehr, Won, Amy Hye, Shi, Tujin, Daude, Nathalie, Lau, Agnes, Young, Rebecca, Xu, Lei, Carlson, George A., Williams, David, Westaway, David, Schmitt-Ulms, Gerold
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749441/
https://www.ncbi.nlm.nih.gov/pubmed/19798432
http://dx.doi.org/10.1371/journal.ppat.1000608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749441/
https://www.ncbi.nlm.nih.gov/pubmed/19798432
http://dx.doi.org/10.1371/journal.ppat.1000608

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