Cargando…

MicroRNA Profiling of BRCA1/2 Mutation-Carrying and Non-Mutation-Carrying High-Grade Serous Carcinomas of Ovary

BACKGROUND: MicroRNAs (miRNA) are 20∼25 nucleotide non-coding RNAs that inhibit the translation of targeted mRNA, and they have been implicated in the development of human malignancies. High grade serous ovarian carcinomas, the most common and lethal subtype of ovarian cancer, can occur sporadically...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Cheng-Han, Subramanian, Subbaya, Beck, Andrew H., Espinosa, Inigo, Senz, Janine, Zhu, Shirley X., Huntsman, David, van de Rijn, Matt, Gilks, C. Blake
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749450/
https://www.ncbi.nlm.nih.gov/pubmed/19798417
http://dx.doi.org/10.1371/journal.pone.0007314