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MicroRNA Profiling of BRCA1/2 Mutation-Carrying and Non-Mutation-Carrying High-Grade Serous Carcinomas of Ovary
BACKGROUND: MicroRNAs (miRNA) are 20∼25 nucleotide non-coding RNAs that inhibit the translation of targeted mRNA, and they have been implicated in the development of human malignancies. High grade serous ovarian carcinomas, the most common and lethal subtype of ovarian cancer, can occur sporadically...
Autores principales: | Lee, Cheng-Han, Subramanian, Subbaya, Beck, Andrew H., Espinosa, Inigo, Senz, Janine, Zhu, Shirley X., Huntsman, David, van de Rijn, Matt, Gilks, C. Blake |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749450/ https://www.ncbi.nlm.nih.gov/pubmed/19798417 http://dx.doi.org/10.1371/journal.pone.0007314 |
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