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Receptor oligomerization and beyond: a case study in bone morphogenetic proteins

BACKGROUND: Transforming growth factor (TGF)β superfamily members transduce signals by oligomerizing two classes of serine/threonine kinase receptors, termed type I and type II. In contrast to the large number of ligands only seven type I and five type II receptors have been identified in mammals, i...

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Detalles Bibliográficos
Autores principales: Heinecke, Kai, Seher, Axel, Schmitz, Werner, Mueller, Thomas D, Sebald, Walter, Nickel, Joachim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749821/
https://www.ncbi.nlm.nih.gov/pubmed/19735544
http://dx.doi.org/10.1186/1741-7007-7-59