cMyc increases cell number through uncoupling of cell division from cell size in CHO cells

BACKGROUND: Over the past decades, the increase in maximal cell numbers for the production of mammalian derived biologics has been in a large part due to the development of optimal feeding strategies. Engineering of the cell line is one of probable approaches for increasing cell numbers in bioreacto...

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Detalles Bibliográficos
Autores principales: Kuystermans, Darrin, Al-Rubeai, Mohamed
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749834/
https://www.ncbi.nlm.nih.gov/pubmed/19735559
http://dx.doi.org/10.1186/1472-6750-9-76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749834/
https://www.ncbi.nlm.nih.gov/pubmed/19735559
http://dx.doi.org/10.1186/1472-6750-9-76

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