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cMyc increases cell number through uncoupling of cell division from cell size in CHO cells
BACKGROUND: Over the past decades, the increase in maximal cell numbers for the production of mammalian derived biologics has been in a large part due to the development of optimal feeding strategies. Engineering of the cell line is one of probable approaches for increasing cell numbers in bioreacto...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749834/ https://www.ncbi.nlm.nih.gov/pubmed/19735559 http://dx.doi.org/10.1186/1472-6750-9-76 |