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Loss of the insulator protein CTCF during nematode evolution

BACKGROUND: The zinc finger (ZF) protein CTCF (CCCTC-binding factor) is highly conserved in Drosophila and vertebrates where it has been shown to mediate chromatin insulation at a genomewide level. A mode of genetic regulation that involves insulators and insulator binding proteins to establish inde...

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Detalles Bibliográficos
Autores principales: Heger, Peter, Marin, Birger, Schierenberg, Einhard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749850/
https://www.ncbi.nlm.nih.gov/pubmed/19712444
http://dx.doi.org/10.1186/1471-2199-10-84