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Rational Extension of the Ribosome Biogenesis Pathway Using Network-Guided Genetics

Biogenesis of ribosomes is an essential cellular process conserved across all eukaryotes and is known to require >170 genes for the assembly, modification, and trafficking of ribosome components through multiple cellular compartments. Despite intensive study, this pathway likely involves many add...

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Detalles Bibliográficos
Autores principales: Li, Zhihua, Lee, Insuk, Moradi, Emily, Hung, Nai-Jung, Johnson, Arlen W., Marcotte, Edward M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749941/
https://www.ncbi.nlm.nih.gov/pubmed/19806183
http://dx.doi.org/10.1371/journal.pbio.1000213