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Rational Extension of the Ribosome Biogenesis Pathway Using Network-Guided Genetics
Biogenesis of ribosomes is an essential cellular process conserved across all eukaryotes and is known to require >170 genes for the assembly, modification, and trafficking of ribosome components through multiple cellular compartments. Despite intensive study, this pathway likely involves many add...
Autores principales: | Li, Zhihua, Lee, Insuk, Moradi, Emily, Hung, Nai-Jung, Johnson, Arlen W., Marcotte, Edward M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749941/ https://www.ncbi.nlm.nih.gov/pubmed/19806183 http://dx.doi.org/10.1371/journal.pbio.1000213 |
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