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Stability of NMDA receptors at the plasma membrane controls synaptic and behavioral adaptations to amphetamine

Plastic changes in glutamatergic synapses that lead to enduring drug craving and addiction are poorly understood. By focusing on the turnover and trafficking of NMDA receptors, we found that chronic exposure to the psychostimulant amphetamine induces selective downregulation of NMDA receptor NR2B su...

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Detalles Bibliográficos
Autores principales: Mao, Li-Min, Wang, Wei, Chu, Xiang-Ping, Zhang, Guo-Chi, Liu, Xian-Yu, Yang, Yuan-Jian, Haines, Michelle, Papasian, Christopher J., Fibuch, Eugene E., Buch, Shilpa, Chen, Jian-Guo, Wang, John Q.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749993/
https://www.ncbi.nlm.nih.gov/pubmed/19349975
http://dx.doi.org/10.1038/nn.2300