Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression

INTRODUCTION: Rho signaling regulates key cellular processes including proliferation, survival, and migration, and it has been implicated in the development of many types of cancer including breast cancer. P190B Rho GTPase activating protein (RhoGAP) functions as a major inhibitor of the Rho GTPases...

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Detalles Bibliográficos
Autores principales: Heckman-Stoddard, Brandy M, Vargo-Gogola, Tracy, McHenry, Peter R, Jiang, Vivian, Herrick, Matthew P, Hilsenbeck, Susan G, Settleman, Jeffrey, Rosen, Jeffrey M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750123/
https://www.ncbi.nlm.nih.gov/pubmed/19703301
http://dx.doi.org/10.1186/bcr2352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750123/
https://www.ncbi.nlm.nih.gov/pubmed/19703301
http://dx.doi.org/10.1186/bcr2352

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