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Targeting the ubiquitin proteasome pathway for the treatment of septic shock in patients
Endotoxic shock is a serious systemic inflammatory response to an external biological stressor. The responsiveness of NF-κB is built upon rapid protein modification and degradation involving the ubiquitin proteasome pathway. Using transgenic mice, we have obtained in vivo evidence that interference...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750148/ https://www.ncbi.nlm.nih.gov/pubmed/19691815 http://dx.doi.org/10.1186/cc7946 |