Foxo1 Links Hyperglycemia to LDL Oxidation and Endothelial Nitric Oxide Synthase Dysfunction in Vascular Endothelial Cells

OBJECTIVE: Atherosclerotic cardiovascular disease is the leading cause of death among people with diabetes. Generation of oxidized LDLs and reduced nitric oxide (NO) availability because of endothelial NO synthase (eNOS) dysfunction are critical events in atherosclerotic plaque formation. Biochemica...

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Detalles Bibliográficos
Autores principales: Tanaka, Jun, Qiang, Li, Banks, Alexander S., Welch, Carrie L., Matsumoto, Michihiro, Kitamura, Tadahiro, Ido-Kitamura, Yukari, DePinho, Ronald A., Accili, Domenico
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750207/
https://www.ncbi.nlm.nih.gov/pubmed/19584310
http://dx.doi.org/10.2337/db09-0167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750207/
https://www.ncbi.nlm.nih.gov/pubmed/19584310
http://dx.doi.org/10.2337/db09-0167

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