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Enterovirus Infection, CXC Chemokine Ligand 10 (CXCL10), and CXCR3 Circuit: A Mechanism of Accelerated β-Cell Failure in Fulminant Type 1 Diabetes

OBJECTIVE: Fulminant type 1 diabetes is characterized by the rapid onset of severe hyperglycemia and ketoacidosis, with subsequent poor prognosis of diabetes complications. Causative mechanisms for accelerated β-cell failure are unclear. RESEARCH DESIGN AND METHODS: Subjects comprised three autopsie...

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Detalles Bibliográficos
Autores principales: Tanaka, Shoichiro, Nishida, Yoriko, Aida, Kaoru, Maruyama, Taro, Shimada, Akira, Suzuki, Masako, Shimura, Hiroki, Takizawa, Soichi, Takahashi, Masashi, Akiyama, Daiichiro, Arai-Yamashita, Sayaka, Furuya, Fumihiko, Kawaguchi, Akio, Kaneshige, Masahiro, Katoh, Ryohei, Endo, Toyoshi, Kobayashi, Tetsuro
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750208/
https://www.ncbi.nlm.nih.gov/pubmed/19641142
http://dx.doi.org/10.2337/db09-0091