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A Variant in the KCNQ1 Gene Predicts Future Type 2 Diabetes and Mediates Impaired Insulin Secretion

OBJECTIVE: Two independent genome-wide association studies for type 2 diabetes in Japanese subjects have recently identified common variants in the KCNQ1 gene that are strongly associated with type 2 diabetes. Here we studied whether a common variant in KCNQ1 would influence BMI as well as insulin s...

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Detalles Bibliográficos
Autores principales: Jonsson, Anna, Isomaa, Bo, Tuomi, Tiinamaija, Taneera, Jalal, Salehi, Albert, Nilsson, Peter, Groop, Leif, Lyssenko, Valeriya
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750226/
https://www.ncbi.nlm.nih.gov/pubmed/19584308
http://dx.doi.org/10.2337/db09-0246