Activation of the AMPK-FOXO3 Pathway Reduces Fatty Acid–Induced Increase in Intracellular Reactive Oxygen Species by Upregulating Thioredoxin

OBJECTIVE: Oxidative stress induced by free fatty acids contributes to the development of cardiovascular diseases in patients with metabolic syndrome. Reducing oxidative stress may attenuate these pathogenic processes. Activation of AMP-activated protein kinase (AMPK) has been reported to reduce int...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Nan, Song, Jun, Zhang, Lin, LeMaire, Scott A., Hou, Xiaoyang, Zhang, Cheng, Coselli, Joseph S., Chen, Li, Wang, Xing Li, Zhang, Yun, Shen, Ying H.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750236/
https://www.ncbi.nlm.nih.gov/pubmed/19592618
http://dx.doi.org/10.2337/db08-1512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750236/
https://www.ncbi.nlm.nih.gov/pubmed/19592618
http://dx.doi.org/10.2337/db08-1512

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