Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells

The receptor-binding domain (RBD) of SARS coronavirus (SARS-CoV) spike (S) protein contains multiple conformation-dependent epitopes that induce neutralizing antibody responses. Here we used CHO-K1 cells to establish a cell line for stable expression of a 193-mer (residues 318–510) RBD (RBD193-CHO)...

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Detalles Bibliográficos
Autores principales: Du, Lanying, Zhao, Guangyu, Li, Lin, He, Yuxian, Zhou, Yusen, Zheng, Bo-Jian, Jiang, Shibo
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750803/
https://www.ncbi.nlm.nih.gov/pubmed/19422787
http://dx.doi.org/10.1016/j.bbrc.2009.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750803/
https://www.ncbi.nlm.nih.gov/pubmed/19422787
http://dx.doi.org/10.1016/j.bbrc.2009.05.003

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