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Downregulation of protease activated receptor expression and cytokine production in P815 cells by RNA interference

BACKGROUND: Protease-activated receptors (PAR) are seven transmembrane G-coupled receptors comprising four genes (PAR-1 ~ PAR-4). Mast cell has been identified to be able to express PARs and release an array of cytokines upon activation. Recently, it was reported that interleukin (IL)-12 could regul...

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Detalles Bibliográficos
Autores principales: Qiao, Liya, Zhang, Huiyun, Wu, Shandong, He, Shaoheng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751739/
https://www.ncbi.nlm.nih.gov/pubmed/19732468
http://dx.doi.org/10.1186/1471-2121-10-62