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Downregulation of protease activated receptor expression and cytokine production in P815 cells by RNA interference
BACKGROUND: Protease-activated receptors (PAR) are seven transmembrane G-coupled receptors comprising four genes (PAR-1 ~ PAR-4). Mast cell has been identified to be able to express PARs and release an array of cytokines upon activation. Recently, it was reported that interleukin (IL)-12 could regul...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751739/ https://www.ncbi.nlm.nih.gov/pubmed/19732468 http://dx.doi.org/10.1186/1471-2121-10-62 |