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Effects of intratracheal administration of nuclear factor-kappaB decoy oligodeoxynucleotides on long-term cigarette smoke-induced lung inflammation and pathology in mice

To determine if nuclear factor-κB (NF-κB) activation may be a key factor in lung inflammation and respiratory dysfunction, we investigated whether NF-κB can be blocked by intratracheal administration of NF-κB decoy oligodeoxynucleotides (ODNs), and whether decoy ODN-mediated NF-κB inhibition can pre...

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Detalles Bibliográficos
Autores principales: Li, Yu-Tao, He, Bei, Wang, Yu-Zhu, Wang, Jing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751757/
https://www.ncbi.nlm.nih.gov/pubmed/19706153
http://dx.doi.org/10.1186/1465-9921-10-79